Article
Genetic evidence for common pathways in human age-related diseases.
Aging cell - 1 Oct 2015
Johnson Simon C, Dong Xiao, Vijg Jan, Suh Yousin
Abstract excerpt
Aging is the single largest risk factor for chronic disease. Studies in model organisms have identified conserved pathways that modulate aging rate and the onset and progression of multiple age-related diseases, suggesting that common pathways of aging may influence age-related diseases in humans as well. To determine whether there is genetic evidence supporting the notion of common pathways underlying...
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