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Conversational Artificial Intelligence-Based Integration of Clinical and Genomic Data Identifies MAPK Alterations in Colorectal Cancer

2025-12-19

Abstract excerpt

<h4>Background</h4> Colorectal cancer (CRC) exhibits marked heterogeneity across age, ancestry, and treatment context, underscored by the rising incidence of early-onset disease (EOCRC). The mitogen-activated protein kinase (MAPK) signaling axis is a central regulator of CRC biology and treatment response, yet the frequency, distribution, and prognostic relevance of MAPK pathway alterations across demographically...

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Literature Corpus work
59b606a1-1e54-5cfe-b0e9-276c83da0de1
DOI
10.64898/2025.12.18.25342607
Open publication

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