Back to search

Article

Artificial Intelligence-Driven Precision Oncology Uncovers Prognostic Significance of RTK-RAS Alterations in FOLFOX-Treated Early-Onset Colorectal Cancer

2025-12-15

Abstract excerpt

The incidence of early-onset colorectal cancer (EOCRC; <50 years) is rising rapidly among populations. Although alterations in the RTK-RAS signaling pathway are central to colorectal cancer (CRC) progression, their prognostic significance in FOLFOX-treated EOCRC remains poorly defined. We analyzed 2,515 CRC cases (H/L = 266; non-Hispanic White [NHW] = 2,249) stratified by ancestry, age at onset, and FOLFOX treatme...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
85b3a370-7b36-50b2-ae00-b94038cda425
DOI
10.64898/2025.12.13.25342208
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Artificial Intelligence-Driven Precision Oncology Uncovers Prognostic Significance of RTK-RAS Alterations in FOLFOX-Treated Early-Onset Colorectal CancerDOI 10.64898/2025.12.13.25342208
Artificial Intelligence Reveals Prognostic TP53 Pathway Alterations in FOLFOX-Treated Early-Onset Colorectal Cancer Among Populations at RiskSemantic proximity
Conversational Artificial Intelligence-Based Integration of Clinical and Genomic Data Identifies MAPK Alterations in Colorectal CancerSemantic proximity
Artificial Intelligence-Enabled Precision Medicine Reveals Prognostic Impact of TGF-Beta Pathway Alterations in FOLFOX-Treated Early-Onset Colorectal Cancer Among Disproportionately Affected PopulationsSemantic proximity
Artificial Intelligence-Enhanced Precision Medicine Reveals Prognostic Impact of TGF-Beta Pathway Alterations in FOLFOX-Treated Early-Onset Colorectal Cancer Among Disproportionately Affected Populations.Semantic proximity
Artificial intelligence for precision oncology: AI-HOPE-MAPK uncovers clinically actionable MAPK alterations in colorectal cancerSemantic proximity
Precision Oncology Through Dialogue: AI-HOPE-RTK-RAS Integrates Clinical and Genomic Insights into RTK-RAS Alterations in Colorectal CancerSemantic proximity
Artificial Intelligence-Enabled Integration Suggests TP53 Pathway Alterations as Prognostic Biomarkers in Populations with Disproportionate Health Burdens.Semantic proximity
Integrating Artificial Intelligence and Precision Medicine to Characterize JAK-STAT Pathway Alterations in FOLFOX-Treated Colorectal Cancer in Disproportionately Affected GroupsSemantic proximity
Artificial intelligence-driven precision medicine identifies prognostic WNT pathway alterations in AA colorectal cancer patients treated with FOLFOXSemantic proximity
Artificial Intelligence Agent: AI-HOPE-TP53 Enables Pathway-Centric Analysis of TP53-Driven Molecular Alterations in Colorectal Cancer Precision OncologySemantic proximity
Artificial Intelligence-Guided Molecular Determinants of PI3K Pathway Alterations in Early-Onset Colorectal Cancer Among High-Risk Groups Receiving FOLFOXSemantic proximity
AI-HOPE: An AI-Driven conversational agent for enhanced clinical and genomic data integration in precision medicine researchSemantic proximity
Select a neighboring publication to make it the new centre.