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From Mutation to Prognosis: AI-HOPE-PI3K Enables Artificial Intelligence-Agent Driven Integration of PI3K Pathway Data in Colorectal Cancer Precision Medicine

2025-05-26

Abstract excerpt

<h4>Introduction</h4> The incidence of early-onset colorectal cancer (EOCRC) is rising rapidly, with disproportionate health burdens falling on populations that experience both the steepest increases and the poorest outcomes. The phosphoinositide 3-kinase (PI3K) signaling pathway is a key oncogenic driver in colorectal cancer (CRC), influencing tumor growth, survival, and therapeutic resistance. Despite its biolo...

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Literature Corpus work
0670d23e-764e-52e5-96d9-da0427b934c7
DOI
10.1101/2025.05.25.25328304
Open publication

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