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Artificial Intelligence-Guided Molecular Determinants of PI3K Pathway Alterations in Early-Onset Colorectal Cancer Among High-Risk Groups Receiving FOLFOX

2025-08-21

Abstract excerpt

<h4>Background</h4> Early-onset colorectal cancer (EOCRC), defined as diagnosis before age 50, is rising rapidly and disproportionately affects high-risk populations, particularly Hispanic/Latino (H/L) individuals, who experience the steepest increases in incidence and mortality. While prevention and screening strategies have curbed late-onset CRC rates, EOCRC remains outside standard screening guidelines and is...

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Literature Corpus work
d95027ab-55f1-5b20-9cb5-5b440833f3ae
DOI
10.1101/2025.08.18.25333929
Open publication

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