Mutations in the Borrelia burgdorferi Flagellar Type III Secretion System Genes <i>fliH</i> and <i>fliI</i> Profoundly Affect Spirochete Flagellar Assembly, Morphology, Motility, Structure, and Cell Division

Abstract excerpt

UNLABELLED: The Lyme disease spirochete Borrelia burgdorferi migrates to distant sites in the tick vectors and mammalian hosts through robust motility and chemotaxis activities. FliH and FliI are two cytoplasmic proteins that play important roles in the type III secretion system (T3SS)-mediated export and assembly of flagellar structural proteins. However, detailed analyses of the roles of FliH and FliI in B....

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