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Article

Morphometric similarity differences in drug‐naive Parkinson's disease correlate with transcriptomic signatures

1 Mar 2024

Abstract excerpt

BACKGROUND: Differences in cortical morphology have been reported in individuals with Parkinson's disease (PD). However, the pathophysiological mechanism of transcriptomic vulnerability in local brain regions remains unclear. OBJECTIVE: This study aimed to characterize the morphometric changes of brain regions in early drug-naive PD patients and uncover the brain-wide gene expression correlates. METHODS: The...

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PMID: 38529533
DOI: 10.1111/cns.14680

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