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Convergent imaging and genetic signatures of gray matter atrophy in Parkinson's disease.

NeuroImage - 1 Sept 2026

Xie Yingying, Dong Zihe, Jiang Yurong, Lin Shiqi, Wang Xinying, Sun Jie, Zhang Ningnannan, Zhang Zhang, Du Jiaojiao, Liu Huaigui, Cao Dairong

Abstract excerpt

Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by widespread structural brain alterations, yet the specific patterns of brain atrophy and their underlying genetic mechanisms remain incompletely understood. Here, we integrated large-scale neuroimaging meta-analysis with population-scale imaging genetics to systematically characterize the genetic architecture linking gray matter...

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PMID: 42336304
DOI: 10.1016/j.neuroimage.2026.122076

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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