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Article

Identification of Novel Genes Associated with Cortical Thickness in Alzheimer's Disease: Systems Biology Approach to Neuroimaging Endophenotype.

Journal of Alzheimer's disease : JAD - 1 Jan 2020

Kim Bo-Hyun, Choi Yong-Ho, Yang Jin-Ju, Kim SangYun, Nho Kwangsik, Lee Jong-Min

Abstract excerpt

Alzheimer's disease (AD) is a common neurodegenerative disorder characterized by a heterogeneous distribution of pathological changes in the brain. Cortical thickness is one of the most sensitive imaging biomarkers for AD representing structural atrophy. The purpose of this study is to identify novel genes associated with cortical thickness. We measured the whole-brain mean cortical thickness from magnetic...

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PMID: 32310165
DOI: 10.3233/JAD-191175

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