Article

Enrichment of a neutrophil-like monocyte transcriptional state in glioblastoma myeloid suppressor cells

2023-12-28

Abstract excerpt

<title>Abstract</title> <p>Glioblastomas (GBM) are lethal central nervous system cancers associated with tumor and systemic immunosuppression. Heterogeneous monocyte myeloid-derived suppressor cells (M-MDSC) are implicated in the altered immune response in GBM, but M-MDSC ontogeny and definitive phenotypic markers are unknown. Using single-cell transcriptomics, we revealed heterogeneity in blood M-MDSC from GBM s...

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Literature Corpus work: 5732ea0a-7d53-5c33-add0-9c51439a3174
DOI: 10.21203/rs.3.rs-3793353/v1

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