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GBMdeconvoluteR accurately infers proportions of neoplastic and immune cell populations from bulk glioblastoma transcriptomics data

2022-11-20

Abstract excerpt

The biological and clinical impact of neoplastic and immune cell type ratios in the glioblastoma (GBM) tumour microenvironment is being realised. Characterising and quantifying cell types within GBMs at scale will facilitate a better understanding of the association between the cellular landscape and tumour phenotypes or clinical correlates. This study aimed to develop a tool that can deconvolute immune and neopla...

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Literature Corpus work
ef19275f-d5f0-547d-8889-1feac066ecbc
DOI
10.1101/2022.11.19.517187
Open publication

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GBMdeconvoluteR accurately infers proportions of neoplastic and immune cell populations from bulk glioblastoma transcriptomics dataDOI 10.1101/2022.11.19.517187
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