Article

Distinct Myeloid Derived Suppressor Cell Populations Promote Tumor Aggression in Glioblastoma

2023-03-27

Abstract excerpt

The diversity of genetic programs and cellular plasticity of glioma-associated myeloid cells, and thus their contribution to tumor growth and immune evasion, is poorly understood. We performed single cell RNA-sequencing of immune and tumor cells from 33 glioma patients of varying tumor grades. We identified two populations characteristic of myeloid derived suppressor cells (MDSC), unique to glioblastoma (GBM) and...

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Literature Corpus work: 186929df-4728-5d79-aa0e-88a20abbd092
DOI: 10.1101/2023.03.26.534192

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