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Hypoxia coordinates the spatial landscape of myeloid cells within glioblastoma to affect outcome

2023-06-30

Abstract excerpt

Myeloid cells are highly prevalent in glioblastoma (GBM), existing in a spectrum of phenotypic and activation states. We currently have limited knowledge of the tumour microenvironment (TME) determinants that influence the localisation and the functions of the diverse myeloid cell populations in GBM. Here we have utilised orthogonal imaging mass cytometry with single cell and spatial transcriptomics approaches to...

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Literature Corpus work
53810321-ecce-5085-a445-42bc2f888136
DOI
10.1101/2023.06.30.547190
Open publication

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Hypoxia coordinates the spatial landscape of myeloid cells within glioblastoma to affect outcomeDOI 10.1101/2023.06.30.547190
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