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Article

The relationship between extreme inter-individual variation in macrophage gene expression and genetic susceptibility to inflammatory bowel disease

2023-08-29

Abstract excerpt

The differentiation of resident intestinal macrophages from blood monocytes depends upon signals from the macrophage colony-stimulating factor receptor (CSF1R). Analysis of genome-wide association studies (GWAS) indicates that dysregulation of macrophage differentiation and response to microorganisms contributes to susceptibility to chronic inflammatory bowel disease (IBD). Here, we analyzed transcriptomic variati...

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Literature Corpus work
568ce9b8-5fff-529c-8506-c4767dd992f5
DOI
10.21203/rs.3.rs-3294385/v1
Open publication

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The relationship between extreme inter-individual variation in macrophage gene expression and genetic susceptibility to inflammatory bowel diseaseDOI 10.21203/rs.3.rs-3294385/v1
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