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Article

Gene coexpression networks reveal a broad role for lncRNAs in inflammatory bowel disease

8 Feb 2024

Abstract excerpt

The role of long noncoding RNAs (lncRNAs) in disease is incompletely understood, but their regulation of inflammation is increasingly appreciated. We addressed the extent of lncRNA involvement in inflammatory bowel disease (IBD) using biopsy-derived RNA-sequencing data from a large cohort of deeply phenotyped patients with IBD. Weighted gene correlation network analysis revealed gene modules of lncRNAs...

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PMID: 38329124
DOI: 10.1172/jci.insight.168988

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