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Article

Genetic risk for Alzheimer’s disease influences neuropathology and cognition via multiple biological pathways

2020-07-17

Abstract excerpt

Alzheimer’s disease is a highly heritable, common neurodegenerative disease characterised neuropathologically by the accumulation of β-amyloid plaques and tau-containing neurofibrillary tangles. In addition to the well-established risk associated with the APOE locus, there has been considerable success in identifying additional genetic variants associated with Alzheimer’s disease. Major challenges in understanding...

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Literature Corpus work
562e4b4a-15fb-5112-bd07-0d628d10a66d
DOI
10.1101/2020.07.16.20149658
Open publication

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Genetic risk for Alzheimer’s disease influences neuropathology and cognition via multiple biological pathwaysDOI 10.1101/2020.07.16.20149658
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