Article

Towards cascading genetic risk in Alzheimer’s disease

2023-12-17

Abstract excerpt

Alzheimer’s disease typically progresses in stages, which have been defined by the presence of disease-specific biomarkers: Amyloid (A), Tau (T) and neurodegeneration (N). This progression of biomarkers has been condensed into the ATN framework, where each of the biomarkers can be either positive (+) or negative (-). Over the past decades genome wide association studies have implicated about 90 different loci invo...

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Literature Corpus work: 3b18c9a4-6fce-58ea-bae7-072292f962bc
DOI: 10.1101/2023.12.16.23300062

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