Article
Genetics of Alzheimer Disease.
Continuum (Minneapolis, Minn.) - 1 Jun 2022
Jayadev Suman
Abstract excerpt
PURPOSE OF REVIEW: This article discusses the spectrum of genetic risk in familial and sporadic forms of early- and late-onset Alzheimer disease (AD). Recent work illuminating the complex genetic architecture of AD is discussed in the context of high and low risk and what is known in different populations. RECENT FINDINGS: A small proportion of AD is autosomal dominant familial AD caused by variants in PSEN1,...
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