Article

Affinity hierarchies and amphiphilic proteins underlie the co-assembly of nucleolar and heterochromatin condensates

2023-09-29

Abstract excerpt

<title>Abstract</title> Nucleoli are surrounded by Pericentromeric Heterochromatin (PCH), reflecting a close spatial association between the two largest biomolecular condensates in eukaryotic nuclei. This nuclear organizational feature is highly conserved and is disrupted in diseased states like senescence, however, the mechanisms driving PCH-nucleolar association are unclear. High-resolution live imaging duri...

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Literature Corpus work: 0410ca7c-b7a4-53a0-8f9d-59632f21fbc4
DOI: 10.21203/rs.3.rs-3385692/v1

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