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Article

Protein phase separation and its role in tumorigenesis.

eLife - 3 Nov 2020

Jiang Shan, Fagman Johan Bourghardt, Chen Changyan, Alberti Simon, Liu Beidong

Abstract excerpt

Cancer is a disease characterized by uncontrolled cell proliferation, but the precise pathological mechanisms underlying tumorigenesis often remain to be elucidated. In recent years, condensates formed by phase separation have emerged as a new principle governing the organization and functional regulation of cells. Increasing evidence links cancer-related mutations to aberrantly altered condensate assembly,...

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Identifiers

PMID: 33138914
DOI: 10.7554/eLife.60264
PMCID: PMC7609067

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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