Article

Determining epitope specificity of T cell receptors with TCRGP

2019-02-06

Abstract excerpt

T cell receptors (TCRs) can recognize various pathogens and consequently start immune responses. TCRs can be sequenced from individuals and methods analyzing the specificity of the TCRs can help us better understand individuals’ immune status in different diseases. We have developed TCRGP, a novel Gaussian process method to predict if TCRs recognize certain epitopes. This method can utilize CDR sequences from TCR...

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Identifiers and source

Literature Corpus work: 55c22ae0-aba3-5151-ada2-da4b7aa4e32c
DOI: 10.1101/542332

Open publication

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