Article

Disease associated human TCR characterization by deep-learning framework TCR-DeepInsight

2023-05-24

Abstract excerpt

<h4>SUMMARY</h4> T cell function is defined by both T cell receptors (TCR) and T cell gene expression (GEX). Although single-cell technology enables the simultaneous capture of TCR and GEX information, the lack of a reference atlas and computational tools hinders our ability to uncover the fundamental TCR usage rules and to efficiently characterize disease-associated TCRs (dTCR). Here, through the collection of m...

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Literature Corpus work: 944f3e97-a7e8-5e28-9196-83fe2fc455ac
DOI: 10.1101/2023.05.22.541406

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