Article

Antigen-specific CD4+ T cells exhibit distinct transcriptional phenotypes in the lymph node and blood following vaccination in humans

2023-09-15

Abstract excerpt

<title>Abstract</title> SARS-CoV-2 infection and mRNA vaccination induce robust CD4+ T cell responses that are critical for the development of protective immunity. Here, we evaluated spike-specific CD4+ T cells in the blood and draining lymph node (dLN) of human subjects following BNT162b2 mRNA vaccination using single-cell transcriptomics. We analyze multiple spike-specific CD4+</su...

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Literature Corpus work: 6bf762c3-4185-5629-a3a7-d11a7a59b9f9
DOI: 10.21203/rs.3.rs-3304466/v1

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