Article

Analysis of regulatory element evolution between human and mouse reveals a lack of <i>cis-trans</i> compensation

2019-11-20

Abstract excerpt

<h4>ABSTRACT</h4> Gene expression differences between species are driven by both cis and trans effects. Whereas cis effects are caused by genetic variants in close proximity to the target gene, trans effects are due to distal genetic variants that affect diffusible elements such as transcription factors. Previous studies have mostly assessed the impact of cis and trans effects at the gene level. However, ho...

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Literature Corpus work: 55af9b26-2303-5424-bbb3-64634e1fe110
DOI: 10.1101/847491

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