Article

Converging molecular evolution in acute myeloid leukaemia

2020-11-04

Abstract excerpt

<h4>SUMMARY</h4> Acute myeloid leukaemia (AML) is a highly heterogeneous disease. Here, we decipher the disease composition of a single AML patient through longitudinal sampling scrutinized by high-resolution genetic and phenotypic approaches, including sequencing, immunophenotyping, ex vivo drug sensitivity testing and establishment of patient-derived xenograft models. Throughout the disease course we identified...

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Literature Corpus work: 54f9ddfe-c1e7-5116-965f-1c849ab0afb3
DOI: 10.1101/2020.11.03.20222885

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