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Article

Clonal evolution of acute myeloid leukemia from diagnosis to relapse

3 Sept 2019

Abstract excerpt

Based on the individual genetic profile, acute myeloid leukemia (AML) patients are classified into clinically meaningful molecular subtypes. However, the mutational profile within these groups is highly heterogeneous and multiple AML subclones may exist in a single patient in parallel. Distinct alterations of single cells may be key factors in providing the fitness to survive in this highly competitive...

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PMID: 31478278
DOI: 10.1002/gcc.22806

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