Article

Multiscale biological interactions define clinical trajectories in acute myeloid leukemia

2026-08-26

Abstract excerpt

Cancer is characterized by complex interactions across genetic, cellular, and microenvironmental scales. However, a quantitative understanding of how these interactions shape clinical trajectories remains limited. Here, we present a multi-scale single-cell dataset from 184 treatment-naive acute myeloid leukemia (AML) patients spanning all major genetic subtypes, together with an analytical framework to dissect int...

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Literature Corpus work: 2c95fbf6-0cf7-51ed-8822-b8b3b52f9258
DOI: 10.64898/2026.08.25.746926

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