Article

Platelet-derived transcription factors license human monocyte inflammation

2022-08-12

Abstract excerpt

<h4>ABSTRACT</h4> CD14 + monocytes, the predominant population in human blood, are primarily engaged in host defense and pro-inflammatory cytokine responses. Aberrant monocyte activity causes life-threatening cytokine storms, while dysfunctional monocytes lead to ’immunoparalysis.’ Understanding the mechanisms controlling monocyte functions is therefore paramount. Here, we reveal platelets’ vital role in human m...

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Literature Corpus work: 54cfff69-cf93-54a0-a11f-a08460b309b8
DOI: 10.1101/2022.08.10.503291

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