Article

Platelets fuel the inflammasome activation of innate immune cells

2019-10-11

Abstract excerpt

<h4>ABSTRACT</h4> The inflammasomes control the bioactivity of pro-inflammatory cytokines of the interleukin (IL)-1 family. The inflammasome assembled by NLRP3 has been predominantly studied in homogenous cell populations in vitro, neglecting the influence of cellular interactions that occur in vivo. Here, we show that platelets, the second most abundant cells in the blood, boost the inflammasome capacity of huma...

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Literature Corpus work: be103fbc-1d3c-58b8-8bf0-13ecdeeca4f9
DOI: 10.1101/800771

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