Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Platelets induce a proinflammatory phenotype in monocytes via the CD147 pathway in rheumatoid arthritis.

Arthritis research & therapy - 18 Nov 2014

Rong Meng-yao, Wang Cong-hua, Wu Zhen-biao, Zeng Wen, Zheng Zhao-hui, Han Qing, Jia Jun-feng, Li Xue-yi, Zhu Ping

Abstract excerpt

INTRODUCTION: Activated platelets exert a proinflammatory action that can be largely ascribed to their ability to interact with monocytes. However, the mechanisms that promote dynamic changes in monocyte subsets in rheumatoid arthritis (RA) have not been clearly identified. The aim of this study was to determine whether platelet activation and the consequent formation of monocyte-platelet aggregates (MPA) might...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arthritis, Rheumatoid
Share to Basigin

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Blood Platelets

Share to Coculture Techniques

Share to Inflammation Mediators

Share to Monocytes

Share to Signal Transduction

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 25404518
DOI: 10.1186/s13075-014-0478-0
PMCID: PMC4298113

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Platelets induce a proinflammatory phenotype in monocytes via the CD147 pathway in rheumatoid arthritis.PMID 25404518Read ↗

Monocyte-platelet interaction induces a pro-inflammatory phenotype in circulating monocytes.Semantic proximity Read ↗

Platelet-derived transcription factors license human monocyte inflammationSemantic proximity Read ↗

Platelet transcription factors license the pro-inflammatory cytokine response of human monocytesSemantic proximity Read ↗

The Role of Monocytes and Macrophages in Autoimmune Diseases: A Comprehensive ReviewSemantic proximity Read ↗

Effects of Notch signaling on the lineage commitment of human peripheral blood monocyte trilineage progenitor under inflammatory conditionsSemantic proximity Read ↗

Functional phenotype of synovial monocytes modulating inflammatory T-cell responses in rheumatoid arthritis (RA).Semantic proximity Read ↗

Activated Platelets Convert CD14+CD16- Into CD14+CD16+ Monocytes With Enhanced FcγR-Mediated Phagocytosis and Skewed M2 Polarization.Semantic proximity Read ↗

Tuning Monocytes and Macrophages for Personalized Therapy and Diagnostic Challenge in Rheumatoid Arthritis.Semantic proximity Read ↗

The role of monocytes in thrombotic disordersSemantic proximity Read ↗

S100A8/A9 drives monocytes towards M2-like macrophage differentiation and associates with M2-like macrophages in osteoarthritic synovium.Semantic proximity Read ↗

Primary human monocytes differentiate into M2 macrophages and involve Notch-1 pathway.Semantic proximity Read ↗

Nanoparticles Targeting Monocytes and Macrophages as Diagnostic and Therapeutic Tools for Autoimmune DiseasesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.