Article

Transcriptional reprogramming from innate immune functions to a pro-thrombotic signature upon SARS-CoV-2 sensing by monocytes in COVID-19

2022-04-03

Abstract excerpt

Alterations in the myeloid immune compartment have been observed in COVID-19, but the specific mechanisms underlying these impairments are not completely understood. Here we examined the functionality of classical CD14 + monocytes as a main myeloid cell component in well-defined cohorts of patients with mild and moderate COVID-19 during the acute phase of infection and compared them to that of healthy individuals...

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Literature Corpus work: f8cca5b5-7bec-5524-9e14-afe4471084f5
DOI: 10.1101/2022.04.03.486830

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