Article

Single-cell analysis identifies monocyte signatures of disease activity and clinical subtypes in Behçet’s disease

2025-12-27

Abstract excerpt

<h4>Objectives</h4> Behçet’s disease (BD) is a multisystem inflammatory disorder with diverse phenotypes and incompletely defined immune mechanisms. This study aimed to map immune dysregulation in BD at high resolution, comparing active versus remission states and identifying pathways linked to clinical phenotypes. <h4>Methods</h4> We performed single-cell RNA sequencing on 247,028 peripheral blood mononuclear c...

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Literature Corpus work: 425d82da-40af-5c1c-8d57-105d785fb1ba
DOI: 10.64898/2025.12.19.25342559

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