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Multicohort Analysis of Publicly-available Monocyte Expression Data Identifies Gene Signatures to Accurately Monitor Subset-specific Changes in Human Diseases

2020-12-22

Abstract excerpt

Monocytes and monocyte-derived cells play important roles in the regulation of inflammation, both as precursors as well as effector cells. Monocytes are heterogeneous and characterized by three distinct subsets in humans. Classical and non-classical monocytes represent the most abundant subsets, each carrying out distinct biological functions. Consequently, altered frequencies of different subsets have been associ...

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Literature Corpus work
befb976e-8a1f-5eb7-90a6-9f2139690fea
DOI
10.1101/2020.12.21.423397
Open publication

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Multicohort Analysis of Publicly-available Monocyte Expression Data Identifies Gene Signatures to Accurately Monitor Subset-specific Changes in Human DiseasesDOI 10.1101/2020.12.21.423397
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