Article
A method to enrich and purify centromeric DNA from human cells
2021-09-24
Abstract excerpt
Centromeres are key elements for chromosome segregation. Canonical centromeres are built over long-stretches of tandem repetitive arrays. Despite being quite abundant compared to other loci, centromere sequences overall still represent only 2 to 5% of the human genome, therefore studying their genetic and epigenetic features is a major challenge. Furthermore, sequencing of centromeric regions requires high coverag...
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Identifiers and source
- Literature Corpus work
- 544349ef-b2b9-5d4c-81b8-b499005feceb
- DOI
- 10.1101/2021.09.24.461328