Article

Predictive Prioritization of Enhancers Associated with Pancreas Disease Risk

2024-09-13

Abstract excerpt

<h4>SUMMARY</h4> Genetic and epigenetic variations in regulatory enhancer elements increase susceptibility to a range of pathologies. Despite recent advances, linking enhancer elements to target genes and predicting transcriptional outcomes of enhancer dysfunction remain significant challenges. Using 3D chromatin conformation assays, we generated an extensive enhancer interaction dataset for the human pancreas, e...

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Literature Corpus work: 5380b2aa-61a6-53d5-b05b-ed37e19b1edf
DOI: 10.1101/2024.09.07.611794

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