Article

Non-CG DNA methylation and MeCP2 stabilize repeated tuning of long genes that distinguish closely related neuron types

2024-01-30

Abstract excerpt

The extraordinary diversity of neuron types in the mammalian brain is delineated at the highest resolution by subtle gene expression differences that may require specialized molecular mechanisms to be maintained. Neurons uniquely express the longest genes in the genome and utilize neuron-enriched non-CG DNA methylation (mCA) together with the Rett syndrome protein, MeCP2, to control gene expression, but the functi...

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Literature Corpus work: 5314b128-e7cf-5ad3-b4e1-97576587479c
DOI: 10.1101/2024.01.30.577861

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Non-CG DNA methylation and MeCP2 stabilize repeated tuning of long genes that distinguish closely related neuron typesDOI 10.1101/2024.01.30.577861Read

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