Article

Comparative single cell epigenomic analysis of gene regulatory programs in the rodent and primate neocortex

2023-04-08

Abstract excerpt

Sequence divergence of cis- regulatory elements drives species-specific traits, but how this manifests in the evolution of the neocortex at the molecular and cellular level remains to be elucidated. We investigated the gene regulatory programs in the primary motor cortex of human, macaque, marmoset, and mouse with single-cell multiomics assays, generating gene expression, chromatin accessibility, DNA methylome, a...

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Literature Corpus work: d64d6022-8e65-5a98-8d9f-cbe0b1d9d23a
DOI: 10.1101/2023.04.08.536119

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