Article

Single-cell Multiome Analysis of Chromatin State and Transcriptome in the Human Basal Ganglia

2026-02-04

Abstract excerpt

<h4>SUMMARY</h4> The basal ganglia play essential roles in motor control, emotion, learning and reward processing. Their dysfunction contributes to many neurological and psychiatric disorders. However, the gene regulatory programs defining basal ganglia cell-type identity and function remain poorly understood, limiting interpretation of disease-associated non-coding variants. Here, we present the first single-cel...

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Literature Corpus work: bbba3f4e-9efe-50d0-aaa6-6026ba8937cd
DOI: 10.64898/2026.02.03.703645

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