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Article

Neurons show distinctive DNA methylation profile and higher interindividual variations compared with non-neurons.

Genome research - 1 May 2011

Iwamoto Kazuya, Bundo Miki, Ueda Junko, Oldham Michael C, Ukai Wataru, Hashimoto Eri, Saito Toshikazu, Geschwind Daniel H, Kato Tadafumi

Abstract excerpt

Epigenome information in mammalian brain cells reflects their developmental history, neuronal activity, and environmental exposures. Studying the epigenetic modifications present in neuronal cells is critical to a more complete understanding of the role of the genome in brain functions. We performed comprehensive DNA methylation analysis in neuronal and non-neuronal nuclei obtained from the human prefrontal...

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Identifiers

PMID: 21467265
DOI: 10.1101/gr.112755.110
PMCID: PMC3083085

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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