Article

Collateral effects of drug resistance evolution: explaining repeatability and directionality patterns

2026-03-27

Abstract excerpt

Drug resistance evolution is hindering the treatment of various diseases. One possible solution could be exploiting trade-offs in resistance to different, existing drugs. Collateral sensitivity means that resistance to one drug increases susceptibility to another. Contrarily, cross-resistance means that resistance to one drug implies resistance to another. These two collateral effects are, however, not always repe...

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Literature Corpus work: 528f41ca-abbd-50ff-a0dc-14334445c0b1
DOI: 10.64898/2026.03.26.714451

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