Article

Dicer deficiency in microglia leads to accelerated demyelination and failed remyelination

2023-10-19

Abstract excerpt

<h4>Summary</h4> Microglia are the resident immune cells of the central nervous system (CNS) and are important regulators of normal brain functions. In CNS demyelinating diseases like multiple sclerosis (MS), the functions of these cells are of particular interest. Here we probed the impact of microRNA (miRNA)-mediated post-transcriptional gene regulation using a mouse model lacking microglia/macrophage-specific...

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Literature Corpus work: 5229f16b-c20c-54ee-84d6-83698bfce09c
DOI: 10.1101/2023.10.17.562812

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