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Article

Epigenetic Modulation of Microglia Function and Phenotypes in Neurodegenerative Diseases.

Neural plasticity - 1 Jan 2021

Wang Li, Yu Chao-Chao, Liu Xin-Yuan, Deng Xiao-Ni, Tian Qing, Du Yan-Jun

Abstract excerpt

Microglia-mediated neuroinflammation is one of the most remarkable hallmarks of neurodegenerative diseases (NDDs), including AD, PD, and ALS. Accumulating evidence indicates that microglia play both neuroprotective and detrimental roles in the onset and progression of NDDs. Yet, the specific mechanisms of action surrounding microglia are not clear. Modulation of microglia function and phenotypes appears to be a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34194489
DOI: 10.1155/2021/9912686
PMCID: PMC8181095

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