Identification of a microglia phenotype supportive of remyelination.

Abstract excerpt

In multiple sclerosis, endogenous oligodendrocyte precursor cells (OPCs) attempt to remyelinate areas of myelin damage. During disease progression, however, these attempts fail. It has been suggested that modulating the inflammatory environment of the lesion might provide a promising therapeutic approach to promote endogenous remyelination. Microglia are known to play a central role in neuroinflammatory...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Demyelinating Diseases
• Share to Disease Models, Animal
• Share to Mice