Article

Integration of Mouse and Human Single-cell RNA Sequencing Infers Spatial Cell-type Composition in Human Brains

2019-01-22

Abstract excerpt

Technical advances have enabled the identification of high-resolution cell types within tissues based on single-cell transcriptomics. However, such analyses are restricted in human brain tissue due to the limited number of brain donors. In this study, we integrate mouse and human data to predict cell-type proportions in human brain tissue, and spatially map the resulting cellular composition. By applying feature s...

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Identifiers and source

Literature Corpus work: 967e90a0-28aa-5265-8d76-fc8bde4b6984
DOI: 10.1101/527499

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