Article

Strategies for cellular deconvolution in human brain RNA sequencing data

2021-08-04

Abstract excerpt

<h4>Background: </h4> Statistical deconvolution strategies have emerged over the past decade to estimate the proportion of various cell populations in homogenate tissue sources like brain using gene expression data. However, no study has been undertaken to assess the extent to which expression-based and DNAm-based cell type composition estimates agree. <h4>Results: </h4>: Using estimated neuronal fractions from D...

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Literature Corpus work: 8acd0987-c932-5cc3-8428-532146979f06
DOI: 10.12688/f1000research.50858.1

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