Article

The <i>TMEM106B</i> rs1990621 protective variant is also associated with increased neuronal proportion

2019-03-20

Abstract excerpt

<h4>Background</h4> In previous studies, we observed decreased neuronal and increased astrocyte proportions in AD cases in parietal brain cortex by using a deconvolution method for bulk RNA-seq. These findings suggested that genetic risk factors associated with AD etiology have a specific effect in the cellular composition of AD brains. The goal of this study is to investigate if there are genetic determinants fo...

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Literature Corpus work: 7cb4b171-1d79-5bc4-a123-e8b70733360f
DOI: 10.1101/583286

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