Article

Strategies for cellular deconvolution in human brain RNA sequencing data

2020-01-20

Abstract excerpt

Statistical deconvolution strategies have emerged over the past decade to estimate the proportion of various cell populations in homogenate tissue sources like brain using gene expression data. Here we show that several existing deconvolution algorithms which estimate the RNA composition of homogenate tissue, relates to the amount of RNA attributable to each cell type, and not the cellular composition relating to...

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Literature Corpus work: 8e4b27a3-93aa-5b1b-8100-922bcb42fc9e
DOI: 10.1101/2020.01.19.910976

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