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Article

A fully joint Bayesian quantitative trait locus mapping of human protein abundance in plasma

2019-01-18

Abstract excerpt

Molecular quantitative trait locus (QTL) analyses are increasingly popular to explore the genetic architecture of complex traits, but existing studies do not leverage shared regulatory patterns and suffer from a large multiplicity burden, which hampers the detection of weak signals such as trans associations. Here, we present a fully multivariate proteomic QTL (pQTL) analysis performed with our recently proposed...

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Literature Corpus work
a42a4b63-8a67-5569-ac3d-9a69d9c29812
DOI
10.1101/524405
Open publication

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A fully joint Bayesian quantitative trait locus mapping of human protein abundance in plasmaDOI 10.1101/524405
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