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Clonal evolution and specificity of the human T follicular helper cell response to <i>Plasmodium falciparum</i> circumsporozoite protein

2021-09-11

Abstract excerpt

<h4>ABSTRACT</h4> T follicular helper (T FH ) cells play a crucial role in the development of long-lived, quality-improved B cell responses after infection and vaccination. However, little is known about their clonal evolution. Here we assessed the cell phenotype, clonal dynamics, and TCR specificity of human circulating T FH (cT FH ) cells at monoclonal level during successive malaria immunizations with radia...

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Literature Corpus work
4f84da13-33d8-56a8-9263-834dd8cd0719
DOI
10.1101/2021.09.10.459751
Open publication

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Clonal evolution and specificity of the human T follicular helper cell response to <i>Plasmodium falciparum</i> circumsporozoite proteinDOI 10.1101/2021.09.10.459751
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