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Th2-like T-follicular helper cells promote functional antibody production during <i>Plasmodium falciparum</i> infection

2020-05-19

Abstract excerpt

The most advanced malaria vaccine only has approximately 30% efficacy in target populations, and avenues to improve next generation vaccines need to be identified. Functional antibodies are key effectors of both vaccine induced and naturally acquired immunity, with induction driven by T-follicular helper cells (TfH) CD4+ T cells. We assessed circulating TfH (cTfH) responses and functional antibody production in hu...

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Literature Corpus work
ef232b3e-ddbe-52c1-a4c0-8b91c74ff7bc
DOI
10.1101/2020.05.18.101048
Open publication

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Th2-like T-follicular helper cells promote functional antibody production during <i>Plasmodium falciparum</i> infectionDOI 10.1101/2020.05.18.101048
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